New Step by Step Map For LDN-27219 pharmacological properties
Just one specially interesting compound is LDN-27219. Though most tTG inhibitors are built to bind on the protein crosslinking active web page, LDN-27219 as a substitute binds for the nucleotide binding pocket on the enzyme although it's in its shut-state conformation, and stabilizes that conformation to circumvent crosslinking activity.78 Schneide